卵巢硬化性间质瘤临床病理特征及鉴别诊断分析

Clinical Pathological Features and Differential Diagnosis of Ovarian Stromal Tumors

目的分析卵巢硬化性间质瘤的临床病理特征及鉴别诊断特点。方法 2010年3月~2015年8月我院接受的卵巢硬化性间质瘤患者有6例,分析其临床病理特征和鉴别诊断特征。结果 3例患者月经不规律,1例患者下腹隆起,有隐痛感,2例无症状;光镜下瘤组织呈假小叶结构,胶原纤维和结缔组织将其肿瘤细胞分为结节状,形状各异,血管丰富,电镜下瘤细胞表现为3种形态;所有患者vimentin、SMA、PR均显示（＋）,CK、EMA均显示（-）。结论卵巢硬化性间质瘤是一种少见的良性肿瘤,需提高对其认识,了解临床病理特征和鉴别诊断特征,从而做到不误诊治。

Objective To analyze the clinicopathologic features and differential diagnosis of ovarian stromal tumors of the ovary. Methods From March 2010 to August 2015,6 cases of patients with ovarian stromal tumors of the ovary in our hospital were treated. The clinical pathological features and differential diagnosis were analyzed. Results 3 cases were irregular,1 cases of patients with lower abdominal bulge,dull pain,2 cases were asymptomatic,optical microscopy of tumor tissue was false lobular structure and collagen fiber and connective tissue will be the tumor cells were divided into nodular,shapes,rich in blood vessels,under the electron microscope,the tumor cells showed as three forms,all patients were positive for vimentin,SMA,PR showed（＋）,CK,EMA showed（-）. Conclusion Ovarian sclerosing stromal tumor is a rare benign tumor,to improve the knowledge,understand the clinicopathological characteristics and differential diagnosis of the characteristics,and thus do not correct diagnosis and treatment.