摘要
随着人类基因测序技术的快速发展,单核苷酸多态性(SNP)[1]在遗传学研究中发挥着重要作用。研究机构在这一研究领域积累了大量的实验数据,如何从海量数据中获取有用信息并实现数据共享是目前亟待解决的问题。本文的目标是构建一个基于SQL Server的二级生物信息学数据库[2]Hu SNP,主要工作包括SNP数据收集、数据库设计和数据存储。SNP数据全部来源于NCBI的Gen Bank,下载的原始数据全部转存到本地数据库中。通过本数据库能够快速检索SNP数据,为人类SNP数据的共享提供了基础的信息服务平台。
Along with the development of the human genome sequencing technology, Single Nucleotide Polymorphism （SNP） has become a key aspect of genetics research. Research institutes have accumulated mass scientific data in these researches and implement of data sharing will promote the development of our researches in this area. The goal of the project is to construct a local SNP database HuSNP based on SQL Server. The main work includes SNP data collection, database design and data storage. The data were collected from GenBank and the downloaded data were shifted into local database for further research. SNP data can be retrieved quickly by the HuSNP database ,it provides a basic service platform for sharin~ human SNP data.
出处
《仪器仪表用户》
2016年第6期31-33,共3页
Instrumentation
