右美托咪定在临床应用中的研究进展被引量：25

Research progress of clinical application of dexmedetomidine

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摘要右美托咪定作为一种新型的高选择性α_2肾上腺素能受体激动剂,拥有镇静、镇痛、抗焦虑、抗交感及呼吸抑制轻等特点,成为临床麻醉中的常用药物。右美托咪定作为全麻辅助用药和区域阻滞中的辅助药物,在心外科、神经外科、儿科和重症监护室中得到普遍应用。本文从右美托咪定的药理学特性和临床应用进行综述。 Dexmedetomidine is a highly selective α-2 adrenoceptor agonist, and possesses hypnotic, sedative,anxiolytic, sympatholytic, and analgesic properties without producing significant respiratory depression. It has become a commonly used drug in clinics especially in cardiovascular surgery,neurological surgery,pediatrics and intensive care unit.The alpha-2 agonist dexmedetomidine is being increasingly used as an adjunctive agent during general and regional anesthesia. Pharmacological characteristics and clinical application of dexmedetomidine are reviewed in this article.

作者马敏李冬梅

机构地区哈尔滨医科大学附属第二医院麻醉科

出处《实用药物与临床》 CAS 2016年第5期644-647,共4页 Practical Pharmacy and Clinical Remedies

关键词右美托咪定麻醉镇静镇痛 Dexmedetomidine Anaesthesia Sedative Analgesia

分类号 R614 [医药卫生—麻醉学]

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参考文献26

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