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活性氧对卵巢癌上皮-间质转化作用研究进展 被引量：4

Progress of the role of reactive oxygen species in epithelial to mesenchymal transition of ovarian cancer
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摘要 上皮-间质转化与上皮性卵巢肿瘤的侵袭和转移密切相关,氧化应激对疾病的发生、发展有重要影响。活性氧作为氧化应激过程中的重要产物,在卵巢癌细胞上皮-间质转化中通过对多种因子的调节参与卵巢癌细胞增殖分化、黏附和迁移等,在卵巢癌的诊断、治疗及预后中有重要作用。本文就活性氧对卵巢癌上皮-间质转化作用的研究进展作一综述。 Epithelial to mesenchymal transition is closely correlated with the invasion and metastasis of epithelial ovarian tumor.Oxidative stress plays an important role in the development and progression of the disease.Reactive oxygen species,as an important product of oxidative stress,participates in the proliferation,differentiation,adhesion and migration process of the ovarian cancer cell by regulating various factors in the process of epithelial to mesenchymal transition,and plays an important role in the diagnosis,treatment and prognosis of ovarian cancer.This paper reviews the research progress of the role of reactive oxygen species in epithelial to mesenchymal transition of ovarian cancer.
作者 殷慧婷 张颖 张玲莉
机构地区 广东医学院 广东医学院附属医院妇产科
出处 《中华实用诊断与治疗杂志》 2016年第6期537-539,共3页 Journal of Chinese Practical Diagnosis and Therapy
基金 广东医学院博士启动项目(B2012038)
关键词 卵巢癌 上皮-间质转化 活性氧 上皮-钙黏蛋白 Ovarian cancer epithelial to mesenchymal transition reactive oxygen species E-cadherin
分类号 R737.31 [医药卫生—肿瘤]
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参考文献22

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二级参考文献22

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共引文献19

同被引文献34

引证文献4

二级引证文献17

中华实用诊断与治疗杂志
2016年 第6期

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