轻量型和标准型聚丙烯补片修补腹股沟无张力疝的效果比较

Effect of lightweight polypropylene mesh versus standard polypropylene mesh on tension-free repair of inguinal hernia

背景:轻量型聚丙烯补片在降低聚丙烯含量的同时加入一些可吸收成分,这些可吸收成分是否会对机体产生不良反应?目的:比较轻量型和标准型聚丙烯补片修补腹股沟无张力疝的效果。方法:将40例男性腹股沟疝患者分为2组,每组20例,试验组采用轻量型聚丙烯补片进行修补,对照组采用标准型聚丙烯补片进行修补。于修补后第2天检测血白细胞计数、中性粒细胞百分比和C-反应蛋白水平,于修补后2 d、1个月、3个月、6个月评估疼痛与不适感,同时记录并发症。结果与结论:两组阴囊水肿、血清肿等并发症发生率比较差异无显著性意义。试验组修复后第2天的白细胞计数、中性粒细胞百分比低于对照组(P<0.05),两组间C-反应蛋白水平比较差异无显著性意义。两组修补后不同时间点的疼痛情况无差异,试验组修补后不同时间点的不适感发生率低于对照组(P<0.05)。结果表明,轻量型聚丙烯补片可降低无张力疝修补后的炎症发应和不适感发生率。

BACKGROUND： Lightweight polypropylene mesh with lower content of polypropylene is added with some absorbable ingredients, and will these ingredients cause adverse reactions in vivo？ OBJECTIVE： To compare the effect of lightweight polypropylene mesh and standard polypropylene mesh on tension-free repair of inguinal hernia. METHODS： Forty patients with inguinal hernia were randomly divided into two groups（n=20 per group）： the patients were treated by lightweight polypropylene mesh as experimental group and those treated by standard polypropylene mesh as control group. At 2 days after surgery, white blood cell counts, neutrophils percentage and level of C-reactive protein were detected. Furthermore, pain scores as well as discomfort incidence and complications were assessed and recorded at 2 days, 1, 3 and 6 months after surgery, respectively. RESULTS AND CONCLUSION： There were no significant differences in postoperative complications between two groups. White blood cell counts and neutrophils percentage in the experimental group were significantly lower than those in the control group（P〈0.05）, but the level of C-reactive protein had no significant difference. Besides, pain scores had no significant difference between the two groups, but the postoperative discomfort incidence in the experimental group was significantly decreased compared with the control group（P〈0.05）. In conclusion, lightweight polypropylene mesh can reduce postoperative inflammation and discomfort incidence.