溃疡性结肠炎重复住院的危险因素分析

The analysis of risk factors in repeatedly hospitalized patients with ulcerative colitis

目的:分析10年间溃疡性结肠炎(UC)住院患者的病历资料,筛选UC患者重复住院可能的危险因素。方法:回顾性调查我院2003年1月至2012年12月期间住院符合UC诊断的115例患者的一般情况、临床资料及重复住院情况。结果:UC患者重复住院率为19.1%(22/115),经多因素Logistic回归分析,饮酒史、幽门螺杆菌(Hp)感染、合并肠外表现者UC重复住院的OR值分别为4.395、4.813、6.261(P<0.05),而维持用药者重复住院的OR值为0.257(P<0.05)。结论:UC患者重复住院率较高,既往饮酒史、Hp感染、合并肠外表现是我院UC患者重复住院可能的危险因素,而维持用药是其保护因素。

Objective： To study the case information of hospitalized patients with ulcerative colitis（ UC） in 10 years,and to filtrate possible risk factors of repeatedly hospitalized patients. Methods： A retrospective study was performed to investigate the general situation,clinical characteristics and the condition of repeatedly hospitalized of115 hospitalized patients with UC from Jan. 2003 to Dec. 2012 in our hospital. Results： 19. 1%（ 22 /115） of the cases had a hospitalized frequency more than one time during ten years. Multivariable logistic regression analysis showed that the OR value of history of drinking,helicobacter pylori（ Hp） infection,extra intestinal manifestations combination in the possible risk factors of repeatedly hospitalized UC patients were 4. 395,4. 813,6. 261（ P〈0. 05）,repectively, while the OR value of sustained medication in the possible risk factors of repeatedly hospitalized was 0. 257（ P〈0. 05）. Conclusion： History of drinking,Hp infection,extra intestinal manifestations combination are the possible risk factors of repeatedly hospitalized UC patients in our hospital,while sustained medication is its protective factor.