联用曲马多和盐酸羟考酮对行剖宫产的产妇进行术后静脉自控镇痛的效果探析

Exploration of effect of using Tramado and oxycodone hydrochloride in combination for the treatment of patient-controlled intravenous analg esia for parturients who accepted caesarean

目的 :探讨联用曲马多注射液和盐酸羟考酮注射液对行剖宫产手术的产妇进行术后静脉自控镇痛的临床效果。方法 :对近年来在我院进行剖宫产手术的75例产妇的临床资料进行回顾性研究。我们根据用药方案的不同将这75例产妇分为参照组、联合1组和联合2组,每组各有25例产妇。我院为参照组产妇单独使用曲马多注射液进行术后静脉自控镇痛,为联合1组产妇联用曲马多注射液和舒芬太尼注射液进行术后静脉自控镇痛,为联合2组产妇联用曲马多注射液和盐酸羟考酮注射液进行术后静脉自控镇痛。然后比较三组产妇术后4h、6h、12h、24h、48h的VAS评分、BCS评分及镇痛的效果。结果 :联合1组与联合2组产妇术后4h、6h、12h、24h、48h的VAS评分均明显低于参照组产妇,其术后4h、6h、12h、24h、48h的BCS评分均明显高于参照组产妇,组间相比差异具有显著性(P<0.05)。联合1组与联合2组产妇镇痛的总有效率均明显高于参照组产妇,且联合2组产妇镇痛的总有效率明显高于联合1组产妇,组间相比差异具有显著性(P<0.05)。结论 :在为行剖宫产的产妇使用曲马多注射液的基础上,联用舒芬太尼注射液或盐酸羟考酮注射液为其进行术后静脉自控镇痛均可取得很好的效果。但联用曲马多注射液和盐酸羟考酮注射液对行剖宫产的产妇进行术后静脉自控镇痛的临床效果更为显著,可有效地降低其VAS评分,提高其BCS评分。

Objective Study of oxycodone hydrochloride injection combined tramadol in cesarean section surgery clinical therapeutic effect of self-control vein analgesia.Method Observation group of 25 patients with oxycodone combined tramadol hydrochloride treatment, while control group of 25 patients with sufentanil combined tramadol treatment, 25 cases of control group were treated by tramadol treatment alone.Result Compared with control group and observation group and control group after the surgery, 4, 6, 12, 24 h VAS score significantly lower, BCS rating increased significantly.Observation group and control group to complete the surgery significantly lower incidence of vomiting. Reference group has three patients used analgesics except analgesia pump, while the observation group and control group did not use.the data contrast difference（P〈0.05）, with statistical significance.Conclusion Joint use of oxycodone hydrochloride injection tramadol in the treatment effect of self-control vein analgesia after cesarean section is obvious,therefore is worth in clinical promotion and application.