济南市冬季灰霾期间儿童唾液溶菌酶浓度分析

Study on concentration of salivary lysozyme of children in dust-haze days of winter in Ji-nan

目的探讨灰霾期间空气污染对儿童唾液溶菌酶的影响,研究唾液溶菌酶的变化规律,为制定、完善和实施空气污染的防治策略提供科学依据。方法济南市12月份灰霾期间选取历城区(污染区)和市中区(清洁区)在校儿童631名,进行唾液溶菌酶含量的检测并测量其身高、体重。结果清洁区儿童唾液溶菌酶浓度显著高于污染区;男、女生唾液溶菌酶含量无明显差异;儿童唾液溶菌酶含量三年级明显低于四、五年级,四、五年级无明显差异;儿童唾液溶菌酶含量与其身高成正相关,与体重无相关性。结论灰霾期间大气污染对反应儿童非特异性免疫功能的唾液溶菌酶有一定影响,仍要长期观察,以了解其中变化规律性。

Objective To explore the impacts of air pollution on salivary lysozyme of children in dust-haze days of winter,the changes and provide scientific basis for developing and improving its prevention and control strategies. Methods Six hundred and thirty-one students in Licheng（polluted area） and Zhongqu（less polluted area） districts of Ji-nan were selected. The concentration of salivary lysozyme of them was detected and their heights and weights were measured in dusthaze days in December. Results The concentrations of salivary lysozyme of the children in less polluted area were higher than those in polluted area. No obvious difference was found in the Lysozyme concentrations between the male and female students. The concentrations of salivary Lysozyme of the children in grade three were significantly lower than those in four and in grade five. There were no difference in those between the children in grade four and grade five. The concentrations of salivary Lysozyme of the children were closely relative to their heights, and no correlation with weights. Conclusion Air pollution during the dust-haze days has impacts on salivary lysozyme of the children reflecting their nonspecific immune function. And a long observation is needed to find out the change regularity.