摘要
目的分析深圳市乙肝免疫预防的成效,为制定乙肝预防控制策略提供科学依据。方法利用乙肝血清流行病学调查结果及历年深圳市乙肝发病数据,采用成本-效益分析方法综合评价深圳市1993-2013年乙肝免疫预防实施成效。结果据估算,深圳市在1993-2013年间共接种10 881 126剂次乙肝疫苗,通过接种乙肝疫苗避免了1 400902例HBs Ag阳性、74 354例急性乙肝、5 577例慢性乙肝、1 032例肝硬化和108例肝癌的发生,产生的净效益为46.91亿元,成本效益比为1∶15.54。结论深圳市在1993-2013年间通过实施乙肝免疫预防为主的综合防制措施取得了显著的经济和社会效益,可以为其他疾病的防控及成本-效益的评价提供参考。
Objective To analyze the effects of hepatitis B vaccination in Shenzhen, and to provide scientific support for formulating proper vaccination strategy. Methods The result of seroepidemiological survey and the data of prevalence of of hepatitis B in Shenzhen were used, and to evaluate the effects of hepatitis B vaccination by cost-benefit analysis from1993 to 2013. Results It is estimated that a 10881126 doses of hepatitis B vaccine were given from 1993 to 2013 in Shenzhen city, by avoiding the 14 00 902 HBs Ag positive, 74 354 cases of acute hepatitis B, 5 577 cases of chronic hepatitis B, 1 032 cases of cirrhosis and 108 cases of liver cancer, the net benefits is 4.691 billion yuan, the ratio of cost/benefit is 1∶15.54. Conclusion Shenzhen city has achieved remarkable economic and social benefits from 1993 to 2013 by means of the implementation of the comprehensive prevention of hepatitis B immune prevention measures, which can provide the reference basis for other diseases prevention and control and the cost-benefit evaluation.
出处
《中国公共卫生管理》
2016年第2期215-217,共3页
Chinese Journal of Public Health Management
关键词
乙型肝炎
乙肝疫苗
成本效益分析
hepatitis B
hepatitis B vaccine
cost-benefit analysis
