宜昌市2006-2013年急性脑膜炎和脑炎病例流行病学分析

Epidemiological analysis of acute cerebral meningitis and encephalitis in Yichang city, 2006-2013

目的建立急性脑膜炎和脑炎(AMES)监测系统,了解其流行病学特征,为疾病防控和临床诊断治疗提供科学依据。方法在宜昌市选取6家监测医院,开展急性脑膜炎和脑炎相关疾病的流行病学调查。结果 2006-2013年宜昌市城区AMES病例占54.7%(1 385/2 532),发病高峰季节出现在5-7月,病例以学生、农民居多,治愈好转率为93.8%(2 374/2 532);病毒性感染占51.9%(1 313/2 532),细菌性感染占15.5%(393/2 532),病因未明病例占26.9%(682/2532)。结论监测系统还需要继续加强和完善,并提高监测的灵敏性。

Objective To carry out the epidemiological surveillance of acute cerebral meningitis and encephalitis and to establish a sensitive acute meningitis and encephalitis surveillance system, in order to provide reference basis for immunization strategy and laboratory support for clinical diagnosis and treatment. Methods Six hospitals were selected as the sentinel surveillance hospitals in Yichang City for epidemiological survey of acute meningitis and encephalitis cases.Results During 2006-2013, 54.7%（1 385/2 532） of AMES cases were in the urban area.The peak season appeared in May to July. Cases were found mostly in students and famers. 1 313 cases（51.9%） had virus infection and 393 cases（26.9%） were due to bacterial infections. The cases of unknown etiology were 682（26.9%）. Conclusion The surveillance and preventive control for AMES surveillance system should be enhanced to improve monitoring sensitivity.