参芎葡萄糖注射液治疗慢性肾脏病的疗效观察

Clinical observation of Shenxiong glucose injection on treating chronic kidney disease

目的观察参芎葡萄糖注射液治疗慢性肾脏病的疗效。方法将收治的70例慢性肾脏病患者随机分成研究组和对照组,每组35例,研究组除接受常规治疗外另使用参芎葡萄糖注射液每日1次静滴,每次100 m L,4周1疗程,对照组仅使用常规治疗。比较治疗前后两组患者的血肌酐(SCr)、血尿素氮(BUN)、血红蛋白(Hb)、血浆粘稠度(PV)、24 h尿蛋白定量(24 h UTP)、纤维蛋白原(FIB)等指标的变化。结果治疗前两组各指标之间的差异无统计学意义(P>0.05),治疗后研究组患者的SCr、BUN、PV、24 h UTP、FIB等参数的含量均明显低于治疗前,差异有统计学意义(P<0.05),对照组上述指标治疗后降低的不明显,差异无统计学意义(P>0.05),研究组有效率为94.29%,对照组有效率为65.72%,研究组的有效率明显高于对照组,差异有统计学意义(P<0.05)。结论参芎葡萄糖注射液能有效治疗慢性肾脏病,延缓患者肾衰竭的发展。

Objective To study the efficacy of Shenxiong glucose injection on treating chronic kidney disease. Methods 70 chronic kidney disease patients were divided into a study group（n = 35） and a control group（n = 35）. The study group received routine treatment added with shenxiong glucose injection 100 m L daily, 4 weeks for one course of treatment, the control group received routine treatment. Observed the changes of Serum creatinine（SCr）,Blood urea nitrogen（BUN）, hemoglobin（Hb）, Plasma viscosity, 24 hours urinary protein and Fibrinogen. Results Such indicators had no significantly differences before treatment between the two groups（P〉 0.05）, while after treatment the serum SCr, BUN, Plasma viscosity, 24 h urinary protein and Fibrinogen had all fallen in the study group and the differences was significantly（P 〈0.05）, while in the control group the changes was not significant（P 〉0.05）. The efficiency of the study group（94.29%） was significantly higher than the control group（65.72%）,（P 〈0.05）. Conclusion Shenxiong glucose injection is effective in treatment of chronic kidney disease.It can delay the development of renal failure.