肺癌肾上腺转移30例分析

Clinical combination therapy for adrenal metastasis from lung cancer

目的 探讨肺癌肾上腺转移的综合治疗效果。方法 回顾性分析 1995年 2月～ 2 0 0 1年 4月间收治的 3 0例肺癌肾上腺转移患者资料 ,其中小细胞肺癌 14例 ,非小细胞肺癌 16例。患者均采用化疗和(或 )放疗 ,18例化疗 +放疗综合治疗 ,12例单纯化疗。结果 全组患者中位生存期 8个月。 12例单纯化疗者中部分缓解 3例 ,有效率为 2 5 .0 % ;18例化疗 +放疗综合治疗者中完全缓解 1例 ,部分缓解 7例 ,有效率为44 .4%。有疼痛症状者放疗后疼痛明显缓解。结论 肺癌肾上腺转移的化疗 +放疗的综合治疗比单一化疗效果更好。

Objective To study the results of combination therapy for adrenal metastasis from lung cancer. Methods Thirty patients with adrenal metastasis were treated in our hospital from Feb. 1995 to Apr. 2001. Forteen patients were small cell lung cancer (SCLC) and 16 patients were non small cell lung cancer (NSCLC). All patients were treated with chemotherapy and/or radiotherapy. Eighteen patients were treated with combination therapy of chemotherapy and radiotherapy, while twelve patients with chemotherapy alone. Results The median survival time was 8 months. The response rate of chemotherapy alone was 25.0% (partial relief 3 cases), while the response rate of combination therapy was 44.4% (complete relief 1 case and partial relief 7 cases). Pain was relieved quickly after radiotherapy for the patients with pain symptom. Conclusion Combination of radiotherapy and chemotherapy is better than chemotherapy alone for the treatment of adrenal metastasis from lung cancer.