vWF及ADAMTS13在肝脏疾病中的意义被引量：1

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摘要微循环障碍参与了多种疾病的进展,例如脓毒症、多器官衰竭等。血管性假性血友病因子（von Willebrand factor,vWF）可使血小板粘附聚集于血管内皮细胞,导致血小板血栓形成;血管性血友病因子特异性裂解酶（a disintegrin-like and metalloprotease with thrombo-spondin type I repeats 13,ADAMTSl3）可裂解vWF多聚体，预防血栓形成.

作者陈亚利许姗姗张晶

机构地区首都医科大学附属北京佑安医院

出处《肝脏》 2016年第4期316-319,共4页 Chinese Hepatology

基金基于数据挖掘的重型肝炎预后判断治疗决策网络系统研究(No.KM201310025008) 基于数据挖掘技术的重型肝炎肝衰竭预后判断模型及治疗决策网络系统的研究(No.CIT&TCD201304178)

关键词肝脏疾病血小板血栓血小板粘附 ADAMTS13 VWF 微循环障碍假性血友病多器官衰竭 Willebrand 脓毒症

分类号 R575 [医药卫生—消化系统]

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