高丝氨酸的合成研究

Synthesis of Homoserine

以γ-丁内酯为原料，通过溴化、水解、氨化反应得到高丝氨酸。反应12h，总收率达70％，该方法具有收率高、反应时间短、条件温和等优点。产物结构经GC—MS，^1HNMR确证。

Homoserine was synthesized via bromination, hydroiysis and amination using gamma-butyrolactone as the starting material. The processing was completed in 12 h and a total yield of up to 70% was obtained. This method had the advantages of high yield, short reaction time and mild reaction conditions. The structure of the final product was characterized using GC-MS and 1H NMR.