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2004至2012年天津市区健康查体人群空腹血糖水平变化趋势及相关因素

Trends and risk factors of blood glucose level in Tianjin urban screening program from 2004 to 2012
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摘要 目的回顾性分析2004至2012年天津市区居民查体数据中空腹血糖(FPG)水平及其相关因素。方法资料来源于天津市肿瘤医院预防医学中心2004至2012年天津市区健康人群体检数据,分析294177名受试者的一般人口学资料、FPG、血甘油三酯(TG)、血总胆固醇(TC)水平等资料。采用Pearson相关分析和Logistic回归分析进行统计学分析。结果从2004至2012年,天津市区居民总体FPG水平呈现随年龄增长而上升的趋势,从15~19岁年龄组的(4.4±0.5)mmol/L增加到70岁以上年龄组的(5.2±1.4)mmol/L,升高了18%。9年内男、女性的FPG异常检出率分别从5.8%(419/7189例)和3.7%(301/8240例)升高到11.9%(3342/28122例)和6.2%(1706/27401例)(P〈0.01),FPG平均水平从2004年男性的(4.6±1.2)mmol/L,女性的(4.5±1.0)mmol/L分别升高到(5.1±1.6)mmol/L和(4.8±1.2)mmol/L。Logistic回归分析示异常FPG的相关因素有性别、年龄、TG和TC[OR和95%CI分别为0.628(0.608~0.649)、1.051(1.050~1.053)、1.237(1.227~1.247)、1.164(1.146~1.182),均P〈0.01]。结论天津市城区居民FPG水平和异常FPG检出率逐年持续升高,男性高于女性,并与年龄、TG和TC水平相关。 Objective To analyze retrospectively the trend of fasting plasma glucose (FPG) levels and related factors in Tianjin urban residents. Methods The data were based on the urban screening program conducted in the Cancer Prevention Center, the Tianjin Cancer Institute and Hospital from 2004 to 2012. The demographic information, FPG, serum triglyceride (TG) and total cholesterol (TC) in 294 177 subjects were measured. Chi square trend test, one way analysis of variance, Pearson analysis and Logistic regression analysis were used for statistical analysis. Results In the period of 2004 to 2012, the blood glucose levels in Tianjin urban residents was increased about 18%with age from (4.4±0.5) mmol/L(in 15-19 yrs group) to (5.2 ± 1.4) mmol/L(in 70 yrs or elder group). During the nine years, the FPG abnormal (higher than upper limit of normal value) detective rates increased from 5.8%(419/7 189) and 3.7%(301/8 240) to 11.9%(3 342/28 122) and 6.2%(1 706/27 401) in male and female respectively(P〈0.01). The mean FPG level for male in 2004 increased from (4.6 ± 1.2) mmol/L to (5.1 ± 1.6) mmol/L in 2012,and from (4.5 ± 1.0) mmol/L to (4.8 ± 1.2) mmol/L for female. Pearson correlation analysis showed that FPG was correlated with gender, age, year, TG and TC (r=-0.078, 0.199, 0.062, 0.167 and 9.138, respectively, all P〈0.001). The related independent factors for abnormal blood glucose were gender, age, TG and TC(the OR and 95%CI was 0.628(0.608, 0.649), 1.051(1.050, 1.053), 1.237(1.227, 1.247), 1.164(1.146, 1.182),respectively, all P〈0.01). Conclusion The FPG levels and abnormal detection rates in Tianjin urban residents continues to rise, especially with higher trend for male than female, which is associated with age, TG and TC levels.
出处 《中华糖尿病杂志》 CAS CSCD 2016年第5期289-293,共5页 CHINESE JOURNAL OF DIABETES MELLITUS
关键词 健康调查 血糖 流行病学 Health surveys Blood glucose Epidemiology
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