卒中相关性肺炎诊疗进展

Progress in the Diagnosis and Treatment of Stroke-associated Pneumonia

卒中相关性肺炎(stroke-associated pneumonia,SAP)是卒中的常见并发症。SAP不但显著延长患者住院时间、增加医疗费用,而且是致残率和致死率升高的重要危险因素。以往观点认为误吸是导致SAP的主要因素,但卒中后免疫功能障碍在SAP发病中的作用日益受到学者的关注。目前尚缺乏国际公认的诊断"金标准",从而制约着相关临床实践与科研工作的开展。本文拟对SAP的诊治进展作一综述。

Stroke-associated pneumonia（SAP） is a kind of common complication of stroke. SAP not only prolongs the length of stay, increases the healthcare costs, but also plays as the important risk factor for the increase of disability rate and mortality. Traditionally, SAP is thought to be secondary to mistaken-aspiration. However, the role of stroke-induced immunodepression in the pathophysiology of SAP has become an increasing concern. Currently, there are no international gold-standard diagnostic criteria for SAP, which has restricted clinical practice and research. This review is to summarize the research progress in the diagnosis and treatment of SAP.