苍耳子化学成分研究

Isolation and Identification of Chemical Constituents from the Fruit of Xanthium Sibiricum Patr.

目的:研究苍耳子的化学成分。方法:采用硅胶柱色谱、ODS反相柱色谱和制备型高效液相色谱等方法分离,从苍耳子70%乙醇提取物的正丁醇萃取组分中分离得到了4个化合物,并通过NMR和MS等波谱方法确定其化学结构。结果:所分离得到的4个化合物分别为2-methyl-3-buten-2-ol-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside(1),3-Methyl-3-butenyl-O-β-Dapiofuranosyl-(1-6)-O-β-D-glucopyranoside(2),3-Methyl-2-butenyl-O-β-D-apiofuranosyl-(1-6)-O-β-D-glucopyranoside(3)和everlastoside C(4)。其中所有化合物均为为首次从苍耳子中分离得到。

Objective： To investigate the chemical constituents from the Fruit of Xanthium sibiricum Patr.. Methods： The chemical constituents were isolated by various isolation methods（ silica gel,ODS and HPLC column chromatography） and their structures were elucidated by the analysis of spectral data（ NMR and MS）. Results： Four compounds were obtained and elucidated as following： 2- methyl- 3- buten- 2- ol- β- D- apiofuranosyl-（ 1- 6）- β- D- glucopyranoside（ 1）,3- Methyl- 3- butenyl- O- β- D- apiofuranosyl-（ 1- 6）- O- β- D- glucopyranoside（ 2）,3- Methyl- 2- butenyl- O- β- D- apiofuranosyl-（ 1- 6）-O- β- D- glucopyranoside（ 3） andeverlastoside C（ 4）. Conclusion： All compounds are reported from the plant for the first time.