苏黄止咳胶囊辅助治疗慢性阻塞性肺疾病急性加重期患者的临床评价

Clinical evaluation of supportive treatment with Suhuangzhike capsules against acute exacerbation of chronic obstructive pulmonary disease

目的：观察苏黄止咳胶囊辅助治疗慢性阻塞性肺疾病急性加重期（AECOPD）患者的临床疗效。方法：将60例AECOPD患者随机分为治疗组和对照组各30例,2组在给予基础药物（抗感染、平喘等药物）治疗的同时,治疗组加用苏黄止咳胶囊,观察2组患者治疗前后症状的改善以及血常规、中性粒细胞和C-反应蛋白的变化。所得数据中定性资料用χ^2检验,定量资料用t检验。结果：治疗组总有效率96.7%（29/30）,对照组总有效率80.0%（24/30）,2组患者治疗后,血常规、中性粒细胞、C-反应蛋白均较治疗前下降（P〈0.05）,且治疗组临床效果优于对照组（P〈0.01）。结论：苏黄止咳胶囊治疗AECOPD患者疗效显著,值得临床推广。

OBJECTIVE To observe clinical efficacy of suhuangzhike capsules in supportive treatment against acute exacerbation of chronic obstructive pulmonary disease（AECOPD）.METHODS Sixty AECOPD patients were randomly divided into treatment group and control group,and each group had 30 patients.Patients of two groups were both treated with essential medicine（antibiotics and antiasthmatics,etc.）.Patients of treatment group received suhuangzhike capsules based on drugs in control group.Symptoms,white blood cell,neutrophils ratio and C reactive protein（CRP）were observed.Qualitative data were assessed with chi-square and quantitative data with t-test.RESULTS Total effective rate was 96.7%（29/30）in treatment group,and 80.0%（24/30）in control group.White blood cell,neutrophils ratio and CRP were both decreased in two groups（P〈0.05）,and clinical effects in treatment group were superior to those in control group（P〈0.01）.CONCLUSION Suhuangzhike capsules against AECOPD are safe and effective,and are worthy of clinical promotion.