帕金森病非痴呆、帕金森病痴呆与阿尔茨海默病患者的命名损害比较

Comparison of naming impairment among patients with Parkinson＇s disease without dementia, Parkinson＇s disease dementia and Alzheimer＇s disease

目的 比较帕金森病（PD）非痴呆、帕金森病痴呆（PDD）与阿尔茨海默病（AD）患者的命名损害特征.方法 收集2011年6月至2013年12月绍兴市人民医院神经内科门诊或住院患者,采用物件命名与动作命名测验分别评定PD非痴呆组（60例）、PDD组（60例）、AD组（60例）以及健康对照组（60例）命名得分情况.结果 物件命名测验总分：PD非痴呆组（40.2±2.8）分,PDD组（36.0±3.1）分,AD组（31.6±4.0）分,健康对照组（44.1±2.2）分,动作命名测验总分：PD非痴呆组（27.3±2.6）分,PDD组（20.5±4.0）分,AD组（22.5±2.7）分,健康对照组（31.6±1.4）分.与健康对照组比较,PD非痴呆患者、PDD与AD患者均存在物件命名与动作命名损害（P＜0.01）.结论 PD非痴呆患者以动作命名损害为主,但物件命名与动作命名损害均较轻,PDD患者动作命名损害最重,AD患者物件命名损害最重.

Objective To compare the characteristics of naming impairment in Parkinson＇s disease （PD） without dementia,Parkinson＇s disease dementia （PDD） and Alzheimer＇s disease （AD）.Methods All participants came from outpatient clinic or inpatients of our hospital during 2011-2013.Object and action naming tests were evaluated among patients with PD without dementia （n =60）,PDD （n =60）,AD （n =60） and healthy control group （n =60）.Results The object naming score of PD without dementia group was 40.2 ± 2.8,PDD group was 36.0 ± 3.1,AD group was 31.6 ± 4.0 and healthy control group was 44.1 ± 2.2,while the action naming score of PD without dementia group was 27.3 ± 2.6,PDD group was 20.5 ±4.0,AD group was 22.5 ± 2.7 and healthy control group was 31.6 ± 1.4.The object and action naming were both impaired in PD without dementia,PDD and AD patients compared with healthy control group （P 〈 0.01）.Conclusions PD patients without dementia have slight object and action naming impairments with more impairments in action naming.Action naming is more impaired in PDD patients,while object naming is more impaired in AD patients.