大剂量奥美拉唑治疗消化性溃疡合并消化道出血的疗效被引量：3

High-dose Omeprazole Curative Effect for the Treatment of Peptic Ulcer with Gastrointestinal Bleeding

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摘要目的探讨消化性溃疡伴消化道出血患者给予大剂量奥美拉唑治疗的疗效。方法选取120例于2012年6月至2013年6月期间我院接收的消化性溃疡合并出血的患者,将患者按药物剂量不同分为常规剂量组与大剂量组,两组均给予奥美拉唑治疗,观察两组疗效。结果大剂量组的临床总有效率明显高于常规剂量组(P<0.05),同时3个月内的再出血率明显低于常规剂量组(P<0.05),服药期间两组未出现严重不良反应。结论消化性溃疡伴消化道出血者采用大剂量奥美拉唑治疗,疗效显著,值得推广。 Objective TO explore the peptic ulcer patients with gastrointestinal bleeding with high-dose omeprazole treatment efficacy.Method Selecting 120 cases in June 2012 to June 2013 our hospital receives patients with bleeding peptic ulcer,and atients at different doses can be divided into regular dose group and high dose group,in the two groups were given omeprazole treatment,observation curative effect of the two groups.Result The clinical total effective rate of high-dose group was obviously higher than that of regular dose group（P〈0.05）,at the same time,3 months and bleeding rate is significantly lower than the conventional dose group（P〈0.05）,two groups did not appear serious adverse events during the medication.Conclusion Peptic ulcer with gastrointestinal bleeding treated with high-dose omeprazole,curative effect is distinct,worthy of promotion.

作者闫卫星

机构地区即墨市移风店镇卫生院

出处《中国医药指南》 2016年第14期9-10,共2页 Guide of China Medicine

关键词大剂量消化性溃疡消化道出血奥美拉唑 Large dosage Peptic ulcer The digestive tract hemorrhage Omeprazole

分类号 R573.2 [医药卫生—消化系统]

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