不同血液净化方式对维持性血液透析患者肾功能的影响

Effects of Different Blood Purification Treatment on Renal Function in Patients with Maintenance Hemodialysis

目的探讨低通量血液透析法、高通量血液透析法对维持性血液透析(MHD)患者残余肾功能(RRF)的影响。方法 33例尿毒症患者接受高通量血液透析器治疗,设为观察组,30例尿毒症患者接受低通量血液透析器治疗,设为对照组,比较治疗前后两组RRF、血清磷、三酰甘油、胆固醇等水平。结果治疗后RRF观察组明显好于对照组,且血清磷、三酰甘油、胆固醇水平改善幅度明显优于对照组(P<0.05)。结论高通量血液透析法对MHD患者RRF影响小,保护作用优于低通量血液透析法。

Objective To discuss the impacts of low flux hemodialysis method and high flux hemodialysis method on residual renal function（RRF） in maintenance hemodialysis（MHD） patients.Methods 33 cases of uremia patients using high-flux hemodialysis dialyzers were set as observation group,30 cases of uremia patients using low-flux hemodialysis dialyzers were set as control group.RRF,serum phosphorus,triglycerides ester,and cholesterol levels in two groups before and after treatment were compared.Results After treatment RRF results in observation group was significantly better than control group,and serum phosphorus,triglyceride,and cholesterol levels improved more significantly than control group（P〈0.05）.Conclusion The high flux hemodialysis method has less impact on RRF in MHD patients,the protective effect of which is better than low flux hemodialysis method.