活性炭联合甘露醇治疗中重度有机磷中毒的疗效观察

Efficacy of Activated Carbon combined with Mannitol Treatment of Moderate to Severe Organophosphate Poisoning

目的研究活性炭联合甘露醇治疗中重度有机磷中毒的疗效观察。方法将101例急诊有机磷中毒患者,随机分为试验组与对照组。对照组50例,采用传统疗法治疗,试验组51例,在对照组的基础上使用活性炭联合甘露醇治疗,观察两组患者服毒至开始抢救时间、入院时胆碱酯酶活力、反跳发生病例数、呼吸衰竭发生病例数、中间综合征(MS)发生病例数、死亡病例数。结果试验组反跳发生病例数、呼吸衰竭发生病例数、中间综合征(MS)发生病例数、死亡病例数均少于对照组,差异有统计学意义(P<0.05)。结论使用活性炭联合甘露醇治疗中重度有机磷中毒效果显著,值得在临床推广。

Objective Discussed the effect of activated carboncombined with mannitol in the treatment of Moderately severe organophosphate poisoning.MethodsSelected 101 patients with moderately severe organophosphate poisoning in the emergency room,were randomly divided into two group,control group 50 patients used of the conventional treatment,experimental group 51 patients in the control group on the basis of using activated carbon combined with mannitol treatment,observe two groups of patients to commit to start to save time,enzyme choline vinegar on admission,bounce cases number,number of respiratory failure cases,intermediate syndrome（MS） in the number of cases,the number of cases of death.Results Experimental group bounce cases number,number of respiratory failure cases,intermediate syndrome（MS） in the number of cases,the number of cases of death number were less than control group（P〈0.05）.Conclusion The use of activated carbon with mannitol therapy moderately severe organophosphate poisoning effect is remarkable,is worth popularizing in clinical.