肝胆显像评价胆囊结石患者肝脏排泄功能的探讨

Analysis of Liver Excretion Function in Patients with Gallbladder Stone

目的利用肝胆显像研究胆囊结石患者肝脏排泄功能的变化。方法回顾性分析97例肝胆动态显像患者资料。研究对象分为正常对照组与胆囊结石组。受试者均进行^(99m)Tc-EHIDA肝胆动态显像并同时测定受试者胆囊排胆分数和肝脏排泄率。1采用t检验分析正常对照组与胆囊结石组间差异。2采用相关分析评价胆囊结石组肝脏排泄功能。结果 1正常对照组与胆囊结石组GBEF显著差异(P<0.01)。2胆囊结石患者肝脏排泄功能与胆囊运动功能呈正相关(P<0.01)。结论胆囊结石患者的肝脏排泄功能降低。

Objective The changes of liver excretion function in patients with gallbladder stone were studied by ^99mTc-EHIDA hepatobiliary scintigraphy. Method The data of 97 cases of patients with hepatobiliary scintigraphy was retrospectively analyzed. The research objects were divided into normal control group and gallstone group. ^99mTc-EHIDA hepatobiliary scintigraphy were performed in the subjects, the gallbladder ejection fraction （GBEF） and the hepatic excretion rate （EX120） of the subjects were also measured in the same time. T test was used to analyze the differences between normal control group and gallstone group. Pearson correlation analysis was used to evaluate the correlation between GBEF and EX120. Result ①GBEF had significant difference between normal control group and gallstone group（P〈0.01）. ②gallstone group EX120 and GBEF gave significantly positively correlated ralationship（γ=0.468, P〈0.01）. Conclusion The liver excretion function in patients with gallbladder stones is reduced.