小儿骶管内复合右美托嘧定术后镇痛效果的观察

Effect of Addition of Dexmedetomidine to Lidocaine and Ropivacaine Caudal Block on Postoperative Analgesia in Children

目的观察小儿骶管内复合右美托咪定的术后镇痛效果。方法 40例6个月～6岁患儿随机分为2组,每组20例。静脉麻醉后利多卡因6 mg/kg,罗哌卡因2 mg/kg,容量0.75 m L/kg行骶管阻滞：A组局麻药中不加其他药,B组局麻药中加入右美托咪定2μg/kg。采用FLACC疼痛评分表进行评分,记录镇痛时间、不良反应。结果 B组的镇痛效果明显优于A组（P〈0.05）。结论 2μg/kg右美托咪定复合利多卡因6 mg/kg,罗哌卡因2 mg/kg,容量0.75 m L/kg行骶管阻滞的术后镇痛效果好,不增加不良反应的发生。

Objective To investigate the effect of addition of dexmedetomidine to lidocaine and ropivacaine caudal block on postoperative analgesia in children. Methods Forty children age 6months to 6 years old were evenly and randomly assigned into two groups in a double-blinded manner. each patient received a single caudal block with lidocaine 6 mg/kg and ropivacaine 2 mg/kg and the total volume 0.75 m L/kg. The local anesthetic solution was added dexmedetomidine 2 μg/kg in group B. Pain scores were evaluated after surgery with the paediatric observational FLACC. The duration of caudal analgesia,and side-effects were recorded. Result Method Group B has a better analgesic effect than Group A（P〈0.05）. Conclusion Addition of dexmedetomidine to lidocaine and ropivacaine caudal block significantly promoted analgesia in children without an increase in incidence of side-effects.