摘要
目的探讨T2期胃癌原发病灶的CT特征及临床病理特征。方法回顾性分析93例经病理证实为T2期胃癌患者的胃壁黏膜厚度及其增强各期ΔCT值的变化,并行单因素分析浅肌层癌(T2a)和深肌层癌(T2b)患者的临床病理特征。结果浅肌层癌(T2a)和深肌层癌(T2b)两组患者在临床病理特征上无统计学意义上的差异(P>0.05)。93例T2期胃癌均显示胃壁有不同程度的增厚。胃癌病变处粘膜厚度(5.44±1.58)mm较正常组粘膜厚度(2.27±0.50)mm明显增厚(t=10.812,P<0.0001)。T2期胃癌与正常对照组间动脉期、门脉期及平衡期ΔCT值比较差异均有统计学意义(t=2.336,P=0.021;t=4.661,P<0.0001;t=3.480,P=0.0001)。结论螺旋CT增强扫描对T2期胃癌诊断具有重要的临床价值。浅肌层癌(T2a)和深肌层癌(T2b)患者临床病理特征上无明显差异。
Objective To study the value of enhanced multiphasic spiral CT（ MDCT） in detection of the T2 gastric cancer and clinicopathology features of the T2 gastric cancer. Methods Ninety three patients were included in our study and underwent MDCT scanning,who were confirmed by pathologic results. The thickness of the mucosa of gastric wall,its changes of enhanced CT value in triphases and also clinicopathology features of the T2 gastric cancer were analyzed. Results There were no statistically significant differences on clinicopathology features among T2 a and T2 b patients（ P〉0. 05）. All ninety three T2 gastric cancer patients showed the thickening of stomach wall with a different degree. The thickness of gastric mucosa（ 5. 44 ± 1. 58） mm in early gastric cancer patients was more thick than that（ 2. 27 ± 0. 50） mm in control group（ t = 10. 812,P〈0. 0001）. There were statistically significant differences in the changes of CT value between T2 gastric cancer patients and normal wall in arterial,portal venous and equilibrium phases（ t = 2. 336,P = 0. 021; t = 4. 661,P〈0. 0001; t = 3. 480,P = 0. 0001）. Conclusion MDCT can provide useful information to improve the diagnosis of T2 gastric cancer. There are no significant differences on clinicopathology features among T2 a and T2 b patients.
出处
《医学影像学杂志》
2016年第5期820-823,共4页
Journal of Medical Imaging
基金
上海交通大学医学院科研基金(No.09XJ21013)
上海市卫生局科研基金(No.2010029 and 2010057)
上海市科学技术委员会科研基金(No.124119a0300)
上海市教育委员会科研基金(No.12Y2034)
江苏省科技计划项目(NO.BL2014064)
