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大环内酯类抗生素在慢性气道炎症疾病治疗中的进展 被引量:7

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摘要 大环内酯类抗生素是第一个被证明能够改变弥漫性泛细支气管炎自然病程的药物,后又被证明除具有抗菌作用外,还兼有抗炎和免疫调节作用,但这种免疫调节作用主要见于14元环和15元环药物,而16元环药物并未显示出明显的免疫调节作用。大环内酯类抗生素口服生物利用度高、组织穿透力强、抗菌谱广,在慢性呼吸道感染疾病中广泛应用。
作者 王文 吴小军
出处 《临床肺科杂志》 2016年第7期1338-1341,共4页 Journal of Clinical Pulmonary Medicine
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