使用无水乙醇作为栓塞材料介入治疗脾功能亢进的疗效

Effect of Interventional Treatment for Hypersplenism with Ethanol as the Embolization Material

目的:观察使用无水乙醇作为栓塞材料行部分脾栓塞术(PSE)治疗脾功能亢进的效果、并发症。方法:使用无水乙醇作为栓塞材料行PSE治疗肝硬化门脉高压性脾功能亢进32例,分别试用无水乙醇2.0 m L 4例、2.5 m L 4例、3.0 m L 3例,之后21例全部采用2.5 m L,分析疗效、并发症、质控效果。结果:32例PSE一次成功,使用无水乙醇2.5 m L栓塞范围较适宜(栓塞部分平均513 m L,约61%)、不良反应较轻、并发症较少,无脾感染发生;随访期无复发病例。结论:PSE使用无水乙醇2.5 m L固定量栓塞法治疗脾亢效果满意、副反应轻,并发症较少,方法简单、费用低。

Objective：To observe the therapeutic effect and complications of Partial Splenic Embolization（PSE）in the treatment of hypersplenism with ethanol as the embolization material. Methods：Ethanol, as an embolization material, was used in the treatment of 32 cases of cirrhosis portal hypertension with PSE with 2.0 mL ethanol for 4 cases, 2.5 mL for 4 cases, 3.0 mL for 3 cases, 2.5 mL for the rest 21 cases. Efficacy, complications, and quality control effect were analyzed among all cases. Results： 32 cases of PSE were successful for the first time. The use of 2.5 mL ethanol embolization was more appropriate（average 513 mL, about area 61%）with less adverse reactions, fewer complications, and no splenic infection. Conclusion： PSE reached a satisfied result using the 2.5 mL fixed amount of ethanol to treat the hypersplenism with mild side reaction, few complications, simple process and low cost.