胰腺实性假乳头状瘤诊治研究新进展

Recent Progress in the Diagnosis and Treatment of Solid Pseudopapillary Tumor of the Pancreas

胰腺实性假乳头状瘤(SPTP)是一种少见的具有恶性潜能或低度恶性的肿瘤,主要见于年轻女性,其临床症状不典型。较成熟的诊断方式是影像学及病理学,可发现肿瘤由实性区、假乳头状区和囊性区组成,病理及免疫组织化学是鉴别SPTP与其他胰腺内、外分泌肿瘤的主要手段。术式应依据术前CT、磁共振成像和术中探查来决定,外科手术是最佳的治疗方法且预后良好,放、化疗的治疗效果不明显。

Solid-pseudopaillary tumor of the pancreas（ SPTP） is an uncommon but distinct pancreatic neoplasm with a low malignancy,typically arise in young women,with non-specific clinical symptoms. The relatively mature diagnosis methods include imaging and pathological examination,which can show that the tumor is a heterogeneous mass with solid,pseudopaillary and cystic components. The pathological and immunohistochemical characteristics are the main methods for the identification of SPTP and other endocrine and exocrine tumors of the pancreas. The procedures should be chosen based on the finding of preoperative CT imaging,MRI imaging and intra-operative exploration of tumor location. Surgery is the optimal treatment for SPTP with good prognosis,while the effect of radiotherapy and chemotherapy is not significant.