255例维吾尔族、汉族、哈萨克族酒依赖患者幽门螺杆菌感染的比较研究

Comparison of Helicobacter pylori infection in the Uygur,Han and Kazakh:a study of 255 patients with alcoholic dependence

目的对255例住院的维吾尔族(简称维族)、汉族、哈萨克族(简称哈族)酒依赖患者幽门螺杆菌(Hp)感染情况进行比较研究,探讨可能的感染途径,为预防提供新思路。方法选取2014年9月至2015年5月住院的符合入组条件的255例酒依赖患者,其中维族77例、汉族90例、哈族88例。采用问卷(包括一般人口学资料和饮酒习惯)和血清Hp-IgG抗体试验比较分析维、汉和哈族患者Hp感染结果。结果汉族Hp感染率为64.44%,维族为80.52%,哈族为78.41%。维、哈族感染率高于汉族,差异有统计学意义(P<0.05),维、哈族之间差异无统计学意义(P>0.05)。Hp感染的维族、汉族和哈族患者在文化程度、职业、初饮年龄、饮酒频率、成瘾年限、每日饮酒量和家族嗜酒史等方面差异均无统计学意义(P>0.05)。Hp感染的维、汉族和哈族患者在共用酒具方面差异有统计学意义(χ2=51.27,P<0.05),维族和哈族共用酒具比例较汉族高。结论不良的生活方式可导致疾病发生,改变过度饮酒的行为,摒弃共用酒具的传统饮酒习惯,对预防Hp感染有积极意义。

Objective To compare the prevalences of Helicobacter pylori（Hp）infection in the patients of the Uygur,Han and Kazakh nationalities as well as to expore possible means of the infection rate of Hp,thus to provide the possible ways for prevention of Hp infection.Methods A total of 255 cases of alcoholic dependence whom were in hospital from Sept.2014 to May.2015 were selected.Among all the individuals,77 of them were the Uygurs,90 people were the Hans and 88 subjects were the Kazakhs.By questionnaires,demographic characteristics and drinking habits were investigated.And by serum Hp-IgG antibody test,the condition of Hp infection in the difference groups were detected.Results Infection rates of Hp in the Han,Uygur and Kazakh were64.44%,80.52% and 78.41%,respectively.The rates of the Uygur and Kazak were significantly higher than that of Han（P〈0.05）,while the difference between the Uygur and Kazakh had no statistic signifcance（P〉0.05）.In addition,the degree of education,careers,age of first alcohol drinking,years of addiction,daily alcohol consumption and family history of alcohol had no differences among the three groups as well（P〉0.05）.The differences of the rate of sharing drinking vessel together（a traditional habit）between the groups of the Uygur,Han and Kazak had statistic significance（χ2=52.27,P〈0.01）.Compared with the Han,rates of sharing drinking vessel together in groups of Uygur and Kazakh were found to be significantly higher（P〈0.05）.ConclusionUnhealthy life styles could lead to the Hp infection.Changing the behavior of excessive drinking and abandoning the traditional habit of drinking may prevent the Hp infection.