摘要
心血管疾病源于多种分子异常，而动脉粥样硬化作为一种炎症性疾病与血脂、血糖等代谢异常密切相关。白藜芦醇是一种抗氧化剂，存在于葡萄皮／籽、红酒及中药虎杖根中。白藜芦醇除了抗氧化、抗炎作用外，对心血管系统也有保护作用，并涉及多分子或信号传导通路，可能成为防治动脉粥样硬化的新药。本文就白藜芦醇的抗氧化抗炎作用及抗动脉粥样硬化研究进展进行综述。
Cardiovascular disease is the result of a variety of molecular abnormalities. As an inflammatory disease, atherosclerosis is closely related to metabolic disorders such as hypercholesterolemia and hyperglycemia. Resveratrol is an antioxidant, which exists in grape skin/seed, red wine, and the root of Polygonum cuspidatum, a traditional Chinese medicinal material. Besides anti-oxidative and anti-inflammatory effects, resveratrol also has protective effects on cardiovascular system through many molecules or signaling pathways. Resveratrol is potential to be a novel drug for preventing and controlling atherosclerosis. This paper summarized the research progresses of resveratrol on its anti-oxidative, anti-inflammatory and anti-atherosclerosis effects.
出处
《中国医药》
2016年第6期932-935,共4页
China Medicine
基金
北京市医院管理局北京市属医院科研培育项目（PX2016007）
天普研究基金（UF201313）
