热毒宁注射液治疗小儿胃肠型上呼吸道感染的效果观察

Effect observation of Reduning injection in the treatment of children with gastrointestinal respiratory tract infection

目的研究热毒宁注射液在小儿胃肠型上呼吸道感染中的临床治疗效果,为提高小儿胃肠型上呼吸道感染治愈率提供依据。方法选取2014年10月-2015年10月医院诊治的36例小儿胃肠型上呼吸道感染患儿资料进行分析,采用随机对照方法将患儿分为对照组和试验组,每组各18例,对照组采用病毒唑注射液治疗,试验组采用热毒宁注射液治疗,比较两组患者临床治疗效果、临床症状改善时间以及不良反应发生率,采用SPSS18.0软件对数据进行统计分析。结果患儿治疗总有效率试验组为94.4%,显著高于对照组的72.2%,差异有统计学意义(P<0.05);试验组患儿治疗后体温恢复正常时间,咽喉症状、胃肠症状改善、咳嗽以及鼻塞流涕消失时间,显著短于对照组,差异有统计学意义(P<0.05);患儿不良反应发生率试验组为11.1%,显著低于对照组的38.9%,差异有统计学意义(P<0.05)。结论小儿胃肠型上呼吸道感染患儿采用热毒宁注射液治疗效果理想,能够提高临床疗效,缩短患儿症状改善时间,药物不良反应发生率低,值得推广应用。

OBJECTIVE To study the clinical effect of Reduning injection in the treatment of children with gastrointestinal respiratory infections,in order to provide evidence for improving the cure rate in children with gastrointestinal respiratory infection.METHODS Clinical data of 36 cases of children with gastrointestinal respiratory tract infection treated in the hospital from Oct.2014-Oct.2015 were analyzed.According to randomized controlled methods,subjects were divided into control and experiment groups,with 18 cases in each group.The control group was given ribavirin injection therapy,experimental group received Reduning injection therapy.Clinical outcomes,clinical symptoms improved time and incidences of adverse reactions in two groups were compared.Data were analyzed with SPSS 18.0.RESULTS The total effective rate of the experimental group was 94.4%,significantly higher than that of control group 72.2%（P〈0.05）.The time for body temperature returned to normal,disappearing time of throat,gastrointestinal symptoms,cough,nasal congestion,and running nose were significantly shorter than the control group（P〈0.05.In experiment,the incidence of adverse reactions was 11.1%,significantly lower than that of control group 38.9%（P〈0.05）.CONCLUSIONChildren with gastrointestinal-type respiratory infections using reduning ideal injection treatment can improve the clinical efficacy and shorten the time of improving symptoms.This medication has a low incidence of adverse drug reactions,so it should be widely applied.