腹泻患儿轮状病毒与腺病毒抗原检测结果分析

Antigen detection of rotavirus and adenovirus in infants with diarrhea

目的了解腹泻患儿粪便标本中轮状病毒和腺病毒的感染情况,为临床治疗提供依据。方法回顾性研究2014年1-12月柳州市妇幼保健院儿科门诊及住院的2 684例腹泻患儿粪便标本中轮状病毒和腺病毒检测结果,并对结果进行统计分析,数据采用SPSS 11.5统计软件进行处理。结果 2 684例腹泻患儿粪便标本中,病毒检测阳性486例,阳性率为18.1%,单纯轮状病毒阳性378例,阳性率14.1%,单纯腺病毒阳性75例,阳性率2.8%,轮状病毒和腺病毒同时阳性33例,阳性率1.2%;6月龄-2岁婴幼儿是轮状病毒感染的高发年龄段,12月份及1月份是轮状病毒感染的高发月份,腺病毒感染全年阳性率较低,每月阳性率均〈5.0%。结论轮状病毒感染是导致婴幼儿腹泻的重要病原,腺病毒感染在婴幼儿腹泻中的致病原作用不可忽视。

OBJECTIVE To investigate the infection status of rotavirus and adenovirus in the stool specimen of infants with diarrhea,provide evidence for clinical treatment.METHODS Test results of rotavirus and adenovirus from the stool specimen from 2684 outpatients and hospitalized patients with diarrhea in the department of Pediatrics of Maternal and Children Health Hospital of Liuzhou from Jan.2014-1-Dec.2014 were retrospectively analyzed.Results were statistically analyzed with SPSS 11.5.RESULTS Of the specimen of 2684 cases,486（18.1%）were found positive for viral infection,including 378（14.1%）cases of rotavirus and 75（2.8%）cases for adenovirus respectively and 33（1.2%）cases for both rotavirus and adenovirus positive.Most of children with rotavirus infections were 6to 24 months.Rotavirus infections occurred mainly in Dec.and Jan.,the yearly positive rate of adenovirus infection was relatively lower than rotavirus,the positive rate of adenovirus was〈5.0% per month.CONCLUSIONRotavirus is one of the most important causes for infant diarrheas,and role of adenovirus infection cannot be ignored in infantile diarrhea.