脑出血早期血肿扩大危险因素分析

Risk Factors of Early Enlargement of Cerebral Hemorrhage

目的探讨脑出血后早期血肿扩大的各种危险因素的相关性。方法前瞻性登记四川省人民医院就诊的所有神经内科、神经外科的脑出血患者。纳入发病24h以内入院接受治疗的自发性脑出血患者,详细收集所有与早期血肿扩大相关的指标,根据血肿是否扩大,将患者分为血肿扩大组(HE)及非血肿扩大组(non-HE,NHE)。结果多因素回归分析结果显示,血肿形态是自发性脑出血患者血肿扩大的独立危险因素,而发病6h内CT检查结果则是判断血肿扩大危险因素的重要依据。结论自发性脑出血患者发病6h内CT检查提示血肿形态越不规则,发生血肿扩大的几率越高。

Objective To discuss the correlation among the risk factors of early enlargement of cerebral hemorrhage. Methods Prospective registration was made to the cases with spontaneous cerebral hemorrhage treated in Department of Neurology and Department of Neurosurgery, Sichuan Provincial People＇s Hospital, the cases within 24 hours of symptom onset were included; all the data related to early enlargement of cerebral hemorrhage were collected; the cases were divided into 2 groups： hematoma enlargement group（HE group） and non-hematoma enlargement group（NHE group）. Results Multivariate Logistic Regression Analysis demonstrated that the hematoma shape was the independent risk factor of hematoma enlargement while the CT scanning within 6 hours of symptom onset was the key basis for determining the risk factor of hematoma enlargement. Conclusions The CT scanning of the cases with spontaneous cerebral hemorrhage made within 6 hours of symptom onset indicates that the more irregular the hematoma shape is, the higher the occurrence of hematoma enlargement will be.