裸花紫珠化学成分研究

Chemical Constituents of Callicarpa Nudiflora

目的研究裸花紫珠的化学成分。方法综合应用各种柱层析方法分离纯化,借助波谱数据和文献资料鉴定化合物的结构。结果分离鉴定了9个化合物,分别为苯丙素类4个：tortoside F（1）、角胡麻苷（2）、6-O-咖啡酰-β-D-葡萄糖（3）、6-O-咖啡酰-α-D-葡萄糖（4）;酚类1个：密花树苷K（5）;黄酮苷类4个：木犀草素-3＇-O-β-D-吡喃葡萄糖苷（6）、金圣草黄素-7-O-β-D-葡萄糖苷（7）、芹菜素-7-O-β-D-葡萄糖苷（8）、木犀草素-3＇-甲氧基-6-羟基-7-O-β-D-吡喃葡萄糖苷（9）。结论化合物1、3~5、7、9为首次从紫珠属植物中分离得到,化合物2为首次从裸花紫珠中分得。

Objective To study the chemical constituents of Callicarpa nudiflora. Methods The chemical constituents were isolated and purified via silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by spectroscopic evidence（ IR,NMR,MS,etc） and compared with those in literature. Results Nine compounds were isolated and identified,including four phenylpropanoids： tortoside F（ 1）,martynoside（ 2）,6-O-caffeyl-β-D-glucopyranose（ 3）,6-O-caffeyl-α-D-glucopyranose（ 4）,one phenolic compound： seguinoside K（ 5）,four flavonoids： luteolin-3＇-O-β-D-glucopyranoside（ 6）,chrysoeriol-7-O-β-D-glucoside（ 7）,apigenin-7-O-β-D-glucoside（ 8）,Luteolin-3＇-methoxyl-6-hydroxy-7-O-β-D-glucopyranoside（ 9）. Conclusion Compounds 1,3- 5,7 and 9 were isolated from this genus for the first time,and compound 2 from this plant for the first time.