连州市普通人群全血中锌、铜水平的调查

Investigation of zinc and copper in blond among general population from Lianzhou

目的调查连州市普通人群血液中锌、铜元素的含量水平,并分析其人群分布特点。方法 2010年-2011年采用分层整群随机抽样的方法,从连州市及其周边乡镇抽取了1 608名对象进行调查并采集其血液和尿液样品。应用电感耦合等离子体质谱法检测血液中锌、铜元素的含量,并分析连州市普通人群血液中锌、铜元素含量在不同年龄、性别的分布特征。结果男性人群血液中锌元素含量与女性人群比较,差异无统计学意义(t=1.10,P=0.27);不同年龄段人群血液中锌元素含量比较,差异具有统计学意义(F=16.34,P<0.01)。男性人群血液中铜元素含量与女性人群比较,差异有统计学意义(t=-5.44,P<0.01);不同年龄段人群血液中铜元素含量差异有统计学意义(F=18.16,P<0.01)。结论本研究调查的数据真实可靠,具有代表性,得到普通人群血液中锌、铜元素含量,填补了连州市这方面基础数据的空缺,为开展进一步科学研究提供科学可靠的参考数据。

Objective To investigate the contents of zinc（ Zn） and copper（ Cu） in blood among general population from Liangzhou City,and to analyze the characteristics of group distribution. Methods From 2010 to 2011,a stratified cluster sampling method was used to investigate 1 608 samples from Lianzhou city and its surrounding towns,and the blood and urine sample were collected. The inductively coupled plasma mass spectrometry（ ICP- MS） was applied to test the content of Zn and copper in blood sample,and the results were used to analyze the characteristics of contents and distributions of Zn and Cu among population of Lianzhou City from different ages,genders and regions groups. Results There is no statistical significance on the difference in the content of zinc in blood between the male and the female group（ t = 1. 10,P = 0. 27）; Compared with the levels of zinc in blood in different age groups,the differences are statistically significant（ F = 16. 34,P〈0. 01）. There is statistical significance on the difference in blood copper content between the male and the female group（ t =- 5. 44,P〈0. 01）; in comparison with blood copper content in different age groups,the differences are statistically significant（ F = 18. 16,P〈0. 01）.Conclusion The data of this investigation are true,reliable and representative,which obtains zinc and copper content in blood from general population,filling the basic data vacancies in Lianzhou,and providing scientific and reliable reference data for further scientific research.