2012-2014年南京地区34家医院常用口服降糖药利用分析

Utilization of Oral Hypoglycemic Drugs in 34 Hospitals in Nanjing from 2012 to 2014

目的：了解南京地区口服降糖药的最新应用近况和发展趋势,为临床合理使用口服降糖药提供参考。方法：根据长江流域医药情报研究所提供的南京地区2012-2014年口服降糖药的销售数据,采用限定日剂量分析法,对该地区34家医院近三年口服降糖药的销售金额、用药频度（DDDs）和限定日费用（DDC）等进行回顾性统计与分析。结果：销售金额排名前三位的药物是阿卡波糖、格列美脲、二甲双胍,DDDs排名前三位的药物是格列美脲、二甲双胍、阿卡波糖,总销售金额和总DDDs均呈逐年增长趋势,销售金额与DDDs的序号比值在0.3~2.3之间。结论：2012-2014年南京地区口服降糖药需求量逐年增加,药物使用符合安全、有效、经济的用药原则。

Objective： To evaluate the utilization and trend of oral hypoglycemic drugs in Nanjing area,and provide clinical references for the rational use of drugs. Methods： According to the sales data of oral hypoglycemic drugs in 34 hospitals in Nanjing area from 2012 to 2014, its utilization was analyzed retrospectively in aspects of consumption sum,DDDs and DDC by means of defined daily dose. Results： The top 3 oral hypoglycemic drugs in the list of consumption sum were acarbose, glimepiride and metformin. In terms of DDDs, glimepiride, metformin and acarbose ranked top 3. The consumption sum and DDDs of oral hypoglycemic drugs increased year by year in Nanjing area. The ratio of serial number of consumption sum and DDDs was from 0.3 to 2.3. Conclusion： The demand of oral hypoglycemic drugs increased year by year from 2012 to 2014, and its utilization conformed to safe,effective and economic principles.