β细胞调节素与糖尿病
摘要
自1993年Shing从小鼠胰腺β细胞瘤细胞中克隆成功β细胞调节素(BTC)以来,受到相关学者的广泛关注,对此进行了大量实验研究,其中研究最多的是BTC与糖尿病的相关性,并取得了可喜的进展。本文就BTC与糖尿病等相关问题的研究概况作一综述。
出处
《滨州职业学院学报》
2007年第4期64-67,共4页
Journal of Binzhou Polytechnic
参考文献12
-
1安家泽,宋振顺,窦科峰,李开宗,韩骅.大鼠β细胞素基因的克隆及其在大肠杆菌中的表达[J].第四军医大学学报,2004,25(23):2141-2143. 被引量:1
-
2S. Thowfeequ,K. L. Ralphs,W.-Y. Yu,J. M. W. Slack,D. Tosh.Betacellulin inhibits amylase and glucagon production and promotes beta cell differentiation in mouse embryonic pancreas[J].Diabetologia.2007(8)
-
3Huotari MA,Miettinen P J,Palgi J,et al.ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture[].The Journal of Endocrinology.2002
-
4Brun T,Franklin I,St-Onge L,et al.The diabetes-linked transcription factor PAX4promotes{beta}-cell prolifera-tion and survival in rat and human islets[].The Journal of Cell Biology.2004
-
5Ogata T,Dunbar A J,Yamamoto Y,et al.Betacellulin-delta4,a novel differentiation factor for pancreatic bata-cells,a meliorates glucose intolerance in streptozotocin-treated rats[].The Journal of Endocrinology.2005
-
6Kitamura R,Ogata T,Tanaka Y,et al.Conophylline and Betacellulin-delta4:an Effective Combination of Differentiation Factors for Pancreatic beta Cells[].Endocrine Journal.2007
-
7Chen S,Ding J,Yu C,et al.Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pan-creatic duodenal homeobox-1[].Gene Therapy.2007
-
8Li L,Yi Z,Seno M,et al.Activin A and betacellulin:effect on regeneration of pancreatic beta-cells in neonatal streptozo-tocin-treated rats[].Diabetes.2004
-
9Thowfeequ S,Ralphs K L,Yu W Y,et al.production and promotes beta cell differentiation in mouse embryonic pancreas[].Diabetologia.2007
-
10Nakagawa T,Furuta H,Sanke T,et al.Molecular scanning of the betacellulin gene for mutations in type2diabetic patients[].Diabetes Research and Clinical Practice.2005
二级参考文献5
-
1Dunbar AJ, Goddard C. Structure-function and biological role of betacellulin[J]. Int J Biochem Cell Biol, 2000;32(8):805-815.
-
2Li L, Yi Z, Seno M, et al. Activin A and betacellulin: Effect on regeneration of pancreatic beta-cells in neonatal streptozotocin-treated rats[J]. Diabetes, 2004;53(3):608-615.
-
3Yamamoto T, Akisue T, Marui T, et al. Expression of betacellulin, heparin-binding epidermal growth factor and epiregulin in human malignant fibrous histiocytoma[J]. Anticancer Res, 2004;24(3b):2007-2010.
-
4Li L, Seno M, Yamada H, et al. Promotion of beta-cell regeneration by betacellulin in ninety percent-pancreatectomized rats[J]. Endocrinology, 2001;142(12):5379-5385.
-
5Li L, Seno M, Yamada H, et al. Betacellulin improves glucose metabolism by promoting conversion of intraislet precursor cells to beta-cells in streptozotocin-treated mice[J]. Am J Physiol Endocrinol Metab, 2003;285(3):E577-E583.
-
1李德桂.β细胞瘤的临床观察及护理[J].中国病案,2005,6(1):44-44.
-
2卢晓.低血糖昏迷附20例临床分析[J].中外医疗,2009,28(14):25-25.
-
3田源,陈璐璐,王咏波,李燕.胰岛β细胞游离脂肪酸受体1表达对胰岛素分泌的影响[J].山东医药,2008,48(48):15-17. 被引量:1
-
4高峰,周汉新,李莉莎,齐晖,李富荣.PDX1和BTC共表达的骨髓间充质干细胞移植治疗大鼠糖尿病的实验研究[J].广东医学,2009,30(6):866-869. 被引量:11
-
5李鸿,周伟斌,李凤英,顾燕云,田璟琰,吴国亭,张迪,周文中,骆天红,李果,罗敏.β细胞素对体外培养大鼠胰岛的影响[J].中华内分泌代谢杂志,2007,23(1):79-80. 被引量:1
-
6于俊霞,田宁艳,杨渭临.β细胞素基因多态性与2型糖尿病的相关性[J].山西医科大学学报,2012,43(10):735-738.
-
7袁文丽,李宜铮,邓德耀.β-细胞素基因多态性与糖尿病的研究进展[J].重庆医学,2014,43(11):1391-1393.
-
8于俊霞,李秀丽,杨渭临.β细胞素基因多态性与2型糖尿病患者血脂异常相关性研究[J].陕西医学杂志,2014,43(1):52-55. 被引量:2
-
9张明明,马倩,王俊明,帖彦青,宋光耀.低密度脂蛋白受体第12外显子基因突变与高胆固醇血症的关系[J].山东医药,2011,51(17):45-46. 被引量:4
-
10邓德耀,袁文丽,刘春林,赵东岩,杨双娟,高宗鹰,徐红云,李奕平,方芳.β细胞素基因-226A>G多态性与糖耐量减低人群的相关性研究[J].中国现代医学杂志,2013,23(14):43-48. 被引量:1