DSA引导下泡沫硬化术与大隐静脉高位结扎联合血管腔内激光术治疗下肢静脉曲张的疗效观察

Contrast effect of foam sclerotherapy of polidocanol and high ligation of great saphenous vein combie with cavity laser surgery for varicose vein of lower extremity

目的探讨DSA引导下聚多卡醇泡沫硬化术与大隐静脉高位结扎术联合血管腔内激光术治疗下肢静脉曲张的临床疗效。方法选取60例下肢静脉曲张患者(共66条腿),随机分为DSA引导下聚多卡醇泡沫硬化术组(A组,30例共33条腿)及大隐静脉高位结扎术联合血管腔内激光术组(B组,30例共33条腿)。分别对两组患者手术时间、住院费用、术后并发症、治疗效果进行对比评价。结果 A组患者手术时间、住院费用明显低于B组(均P<0.01);A组患者术后皮下瘀血、感觉麻木、皮下脂肪液化感染、皮肤灼伤的发生率均显著低于B组(均P<0.01);两组患者静脉炎的发生率差异无统计学意义(P>0.05);两组患者出院时及术后3个月、6个月、1年治疗效果比较差异均无统计学意义(均P>0.05)。结论 DSA引导下聚多卡醇泡沫硬化剂治疗下肢静脉曲张是一项创伤小、并发症少、安全、有效的治疗方法。

Objective To explore the clinical effect of foam sclerotherapy of polidocanol and high ligation of great saphenous vein combie with cavity laser surgery for varicose vein of lower extremity.Methods A total of 60 cases（66 diseased limbs）of varicose vein of lower extremity patients were randomly divided into two groups, A group treated with foam sclerotherapy of polidocanol （n=30, 33 diseased limbs） , B group treated with high ligation of great saphenous vein combie with cavity laser surgery （n=30, 33 diseased limbs）. The operation time, hospitalization expenses, the incidence of complications and the treatment effect were compared.Results The operation time and hospitalization expenses of A group signiifcantly lower than B group,there was signiifcant difference（P〈0.01）;The incidence of complications of A group including ecchymoma, sense of paralysis, subcutaneous infection and skin burns were lower than B group, there was significant difference（P〈0.01）. There was no significant difference in occurrence rate of phlebitis between two groups （P〉0.05）. There was no significantly statistical difference in treatment effect of two groups（leaving hospital, after 3 months, after 6 months, after 1 year）（P〉0.05）. Conclusions Foam sclerotherapy of polidocanol is a microinvasive, fewer complications, safe, effective treatment for varicose vein of lower extremity.