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不可忽视利奈唑胺引起的血小板减少 被引量:4

Platelets can not be Ignored due to Reduction in Linezolid
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摘要 本文中1例因重症肺炎引起肾功能不全的患者在使用利奈唑胺过程中发生严重血小板下降。尽管已对血小板的指标进行了监测,但由于对该药可引发严重血小板下降的原因认识不足,仍然发生了较严重的不良反应。故对利奈唑胺在肾功不全患者的使用过程中,一旦出现血小板减少需高度警惕,当低于正常值或基础值的25%时须及时停药,以保证临床安全用药的安全性。 In this paper, 1 cases of severe pneumonia caused by renal insufficiency occurred in patients with the use of linezolid in the process of severe thrombocytopenia was reported. In spite of platelet parameters were monitored, due to the severe thrombocytopenia may caused by the drug, and other serious adverse reactions, more attention should be paid for those people with renal dysfunction with the use of linezolid. Once thrombocytopenia appears, it requires a high degree of vigilance. When it is less than 25% of normal values or basic values, the patient shall stop the medicine promptly, in order to ensure the safety of clinical medication safety.
作者 胡小玲 严毅
出处 《药品评价》 CAS 2016年第8期60-62,共3页 Drug Evaluation
关键词 利奈唑胺 血小板减少 肾功能不全 Linezolid Platelet Renal Insufficiency
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参考文献9

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二级参考文献87

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