中医综合治疗代偿期肝硬化40例临床观察

Clinical observation of TCM comprehensive treatment in treating 40 cases hepatic cirrhosis in compensatory stage

目的:中医综合治疗代偿期肝硬化40例进行临床观察。方法:选择我院2014年2月—2015年2月所收治的80例代偿期肝硬化患者,有40例患者为低病毒载量,有40例患者为高病毒载量。基于随机数字法又可将高、低病毒载量组分为对照组及中医组,各20例,对其进行治疗。结果:高病毒载量患者中中医组的治疗有效率为95.0%,而对照组为70.0%,二者存在着较为明显的差异,具有统计学意义(P<0.05)。低病毒载量患者中中医组的治疗有效率为95.0%,而对照组为65.0%,二者存在着较为明显的差异,具有统计学意义(P<0.05)。高病毒载量组中医组与对照组HBV-DNA测定值在治疗后都大幅度降低,但二者之间无明显差异,不具有统计学意义(P>0.05)。结论:中医综合治疗代偿期肝硬化效果较佳,副作用小,值得推广应用。

Objective: To observe the clinical effect of TCM comprehensive treatment in treating 40 cases hepatic cirrhosis in compensatory stage. Methods: 80 patients with hepatic cirrhosis in compensatory stage admitted and treated in our hospital from February 2014 to February 2015 were selected, 40 patients were with high viral load and 40 patients were with low viral load, high viral load group and low viral load group were further randomly divided into the control group and TCM group, with 20 cases in each group. All the patients receive treatment. Results: The effective rate of the TCM group and the control group in high viral load group was 95.0% and 70.0% respectively, there was significant difference and the difference was statistically significant(P<0.05). The effective rate of the TCM group and the control group in low viral load group was 95.0% and 65.0% respectively, there was significant difference and the difference was statistically significant(P<0.05). The HBV-DNA detection value of the TCM group and the control group in high viral load group decreased significantly after treatment, but there was no significant difference and the difference was not statistically significant(P>0.05). Conclusion: TCM comprehensive treatment had better therapeutic effect and little side effect in treating hepatic cirrhosis in compensatory stage and it was worthy of promoting and application.