摘要
1 例78 岁男性患者,因无明显诱因出现心前区刀割样疼痛伴出冷汗,持续约2 - 3 h,后因心前区隐痛不适20 h 后入院就诊.拟急性冠脉综合征收住我院.入院后给予阿托伐他汀钙片（20 mg,qd）稳定斑块、调脂,改善微循环等.该患者服用阿托伐他汀钙片第3 天,出现精神异常、胡言乱语、躁动不安、对答不切题,无头痛、恶心、呕吐,无畏寒发热、四肢乏力,病理征阴性,考虑为阿托伐他汀钙片引起的药品不良反应,遂停用阿托伐他汀钙片,停药2 d 后患者上述症状缓解,停药4 d后无不适症状.
One 78-year-old male patient admitted to hospital due to precordial pain for 20 hours, precordial lancinating pain with cold sweat for about 2 – 3 hours. The patient was diagnosed as acute coronary syndrome. The patient was treated with atorvastatin calcium tablet 20 mg to stabilize plaque, regulate blood lipids and improve microcirculation, etc. After 3 days, the patient suffered with mental disorder, talking nonsense, restlessness, giving irrelevant answers without headache, nausea, vomiting, fever, chills and weakness. The pathology was negative. Giving the adverse drug reaction was caused by atorvastatin calcium, the medicine was stopped. After 2 days, the symptoms of mental disorder relieved and disappeared with no recurrence 4 days later.
出处
《中国药物应用与监测》
CAS
2016年第3期193-194,共2页
Chinese Journal of Drug Application and Monitoring
关键词
阿托伐他汀钙
精神异常
药品不良反应
Atorvastatin calcium
Mental disorder
Adverse drug reaction
