鼻喷激素治疗儿童重度腺样体肥大致鼻堵效果观察

目的探讨鼻喷激素对儿童中重度腺样体肥大导致鼻堵效果。方法将60例（3~7岁）经鼻内镜诊断为腺样体重度肥大且没有药物治疗史的患儿随机分为2组,各30例。第1组（治疗组）使用鼻喷激素（糠酸莫米松）,第2组（对照组）使用生理盐水。治疗3个月后观察鼻堵改善情况。采用患儿家长填写问卷评估主观鼻堵情况,鼻内镜检查腺样体占后鼻孔面积评估客观治疗后腺样体肥大鼻堵效果。结果 2组患者治疗后鼻堵均有一定缓解,但鼻喷激素治疗组鼻堵改善明显,2组间差异有统计学意义（P〈0.01）。结论鼻喷激素（糠酸莫米松）对于儿童重度腺样体肥大导致鼻堵有一定短期治疗效果。

Objective To assess the efficacy of intranasal corticosteroids for improving nasal airway obstruction in children with severeadenoidal hypertrophy. Methods Sixty cases of endoscopic severe adenoidal hypertrophy aged 3-7 years no history of medical treatment wereenrolled in this study. All the cases were randomly divided into two groups. Group 1 （study group） was received mometasonefuroate nasal spray for 3months, and Group 2 （control group） was underwent saline nasal spray for the same period. All the patients were assessed with clinical scoring systemwhich was obtained from the parents with a questionnaire. The adenoid size was evaluated using endoscope. And the ratio of the area of the adenoidrelative to the area of the posterior choana was measured to assess the degree of adenoidal hypertrophy. Results Resolution of nasal obstruction instudy group were statistical significantly higher as compared control group （P〈0. 01）. Conclusion It is effective that intranasal corticosteroids sprayin the treatment of nasal airway obstruction in children with severe adenoidal hypertrophy in short period.