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Infrared autofluorescence, short-wave autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytomas 被引量:3

Infrared autofluorescence, short-wave autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytomas
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摘要 AIM: To investigate the findings of infrared fundus autofluorescence(IR-AF) and spectral-domain optical coherence tomography(SD-OCT) in eyes with optic disc melanocytoma(ODM).· METHODS: IR-AF findings and those of other ophthalmologic imaging examinations, including short-wave autofluorescence(SW-AF), fluorescein angiography(FA), fundus color photography, and SD-OCT of 8 eyes of 8 consecutive cases with ODM were assessed.·RESULTS: The ODMs in all cases(100%) presented similar IR-AF, SW-AF, and FA findings. On IR-AF images, ODMs showed outstanding hyper-AF with well-defined outline. On SW-AF images, the area of ODMs presented as hypo-AF. FA images revealed the leaking retinal telangiectasia on the surface of the ODMs. On SDOCT images in 8 cases(100%), the ODMs were sloped with highly reflective surface, which were disorganized retina and optic nerve layers. In 7 cases(87.5%), peripapillary choroids were involved. The melanocytomas of 8 cases(100%) presented as optically empty spaces. Vitreous seeds were found in one case(12.5%).· CONCLUSION: IR-AF imaging may provide a new modality to evaluate the pathologic features of ODMs,and together with SW-AF imaging, offers a new tool to study biological characteristics associated with ODMs.SD-OCT is a valuable tool in delimitating the tumor extension and providing morphological information about the adjacent retinal tissue. AIM: To investigate the findings of infrared fundus autofluorescence(IR-AF) and spectral-domain optical coherence tomography(SD-OCT) in eyes with optic disc melanocytoma(ODM).· METHODS: IR-AF findings and those of other ophthalmologic imaging examinations, including short-wave autofluorescence(SW-AF), fluorescein angiography(FA), fundus color photography, and SD-OCT of 8 eyes of 8 consecutive cases with ODM were assessed.·RESULTS: The ODMs in all cases(100%) presented similar IR-AF, SW-AF, and FA findings. On IR-AF images, ODMs showed outstanding hyper-AF with well-defined outline. On SW-AF images, the area of ODMs presented as hypo-AF. FA images revealed the leaking retinal telangiectasia on the surface of the ODMs. On SDOCT images in 8 cases(100%), the ODMs were sloped with highly reflective surface, which were disorganized retina and optic nerve layers. In 7 cases(87.5%), peripapillary choroids were involved. The melanocytomas of 8 cases(100%) presented as optically empty spaces. Vitreous seeds were found in one case(12.5%).· CONCLUSION: IR-AF imaging may provide a new modality to evaluate the pathologic features of ODMs,and together with SW-AF imaging, offers a new tool to study biological characteristics associated with ODMs.SD-OCT is a valuable tool in delimitating the tumor extension and providing morphological information about the adjacent retinal tissue.
出处 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2016年第5期713-716,共4页 国际眼科杂志(英文版)
关键词 MELANOCYTOMA ANGIOGRAPHY AUTOFLUORESCENCE optical coherence tomography melanocytoma angiography autofluorescence optical coherence tomography
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