经椎弓根椎体内植骨治疗老年骨质疏松性脊柱骨折的疗效分析

Curative effect analysis of transpedicular intrabody grafting in the treatment of senile osteoporoticvertebral fracture

目的探讨经椎弓根椎体内植骨治疗老年骨质疏松性脊柱骨折的疗效。方法收集我院2013年1月至2014年9月入院的80例老年骨质疏松性脊柱骨折患者随机分为两组，对照组患者采用单纯短节段弓根钉棒系统内固定治疗，实验组采用经椎弓根椎体内植骨治疗，比较两组患者治疗前后椎体高度、Cobb角、疼痛程度与相关临床指标。结果实验组患者椎体高度术后丢失[（4．86±0．81）％]与术后Cobb角水平[（3．85±0．68）°]均显著低于对照组[（7．35±1．24）％，（7．55±1．17）°]，差异有统计学意义（P〈0．01）。实验组患者术后VAS评分[（1.89±0．52）]显著低于对照组[（5．03±1．67）1，差异有统计学意义（P〈0．01）。实验组患者末次随访椎体高度丢失[（4．77±1．16）％]与末次随访Cobb角水平[（5．19±1．09）°]显著低于对照组[（11．63±4．59）％，（11．42±3．96）°]，差异有统计学意义（P〈0．01）。结论经椎弓根椎体内植骨治疗老年骨质疏松性脊柱骨折的疗效显著，具有借鉴性。

Objective To investigate the curative effect of transpedicular intrabody grafting in the treatment of senile osteoporotic vertebral fracture. Methods 80 cases of senile osteoporotic vertebral fracture admitted in our hospital from January 2013 to September 2014 were collected and randomly divided into two groups. Control group was treated with simple short-segment pedicle screw system fixation, while experimental group was treated with transpedicular intrabody grafting. The vertebral height, Cobb＇s angle, pain degree and other correlated clinical indexes of two groups before and after treatment were compared. Results Postoperative lost vertebral height, Cobb＇s angle, VAS score of experimental group were significantly lower than those of control group [（4.86±0.81 ）% vs.（7.35± 1.24）%, （3.85±0.68）°vs.（7.55± 1.17）°, （1.89±0.52） vs.（5.03± 1.67）], with statistically significant differences （P〈0.01）. The lost vertebral height and Cobb＇s angle at the last follow-up of experimental group were significantly lower than those of control group [（4.77± 1.16）% vs.（11.63±4.59）%, （4.59± 1.09）°vs. （11.42±3.96）°], with statistically significant differences （P〈0.01）. Conclusion Transpedicular intrabody grafting has significant curative effect in the treatment of senile osteoporotic vertebral fracture, which is of reference in clinical oraetice.