中孕早期胎儿先天性心脏病筛查中四维超声时空关联成像技术的临床应用效果观察

Observation on the clinical application effect of four dimensional ultrasound in screening of fetal congenital heart disease in early pregnancy

目的探讨中孕早期胎儿先天性心脏病筛查中四维超声时空关联成像技术的临床应用效果。方法以1200例孕妇为研究对象,均先后行二维超声扫描及STIC筛查。分析其随访结果和比较各项检测方式的敏感性和特异性水平。结果联合检测诊断CHD的敏感性水平、特异性水平及阳性预测值均显著高于常规二维超声及STIC技术单一检测,两两比较差异具有统计学意义(P<0.05)。另,联合检测诊断CHD的阴性预测值高达99.9%。结论四维超声时空关联成像技术应用于CHD病症的诊断在临床上,可提高诊断效率,漏诊率及误诊率均较低,优势明显,值得推广。

Objective To investigate the clinical effect of four dimensional ultrasound imaging technique in the screening of early fetal congenital heart disease.Method 1200 cases of pregnant women were selected as the research object,after the first two dimensional ultrasound scanning and STIC screening.Analyzed the follow-up results and comparison of the sensitivity and specificity of the detection methods.Results Combined detection in the diagnosis of CHD sensitivity level,level of specificity and positive predictive value were significantly higher than those of conventional ultrasonography and stic single detection,the pairwise differences with statistical significance（P 〈0.05）.In addition,the negative predictive value of combined detection and diagnosis of CHD was up to 99.9%.Conclusions The application of four-dimensional ultrasound imaging technology in the diagnosis of CHD disease,can improve the diagnostic efficiency,missed diagnosis rate and misdiagnosis rate are low,obvious advantages,it is worth promoting.