聚维酮碘稀释液预防坏疽性阑尾炎伴穿孔术后腹腔及切口感染中的临床观察

Clinical observation of gan grenous perforated appendicitis with postoperative abdominal cavity and incision infection by washing abdominal cavity with povidone iodine diluent

目的:探讨聚维酮碘稀释液在预防坏疽性阑尾炎伴穿孔术后腹腔及切口感染的临床疗效,为临床治疗提供参考。方法:回顾性分析我院收治的120例坏疽性阑尾炎伴穿孔患者临床资料,根据术中腹腔及切口冲洗方法不同,分为A组(聚维酮碘稀释液)、B组(甲硝唑)及C组(生理盐水),各40例,观察三组患者术后腹腔及切口感染发生率、术后住院时间、体温恢复正常时间、肛门排气时间及不良反应发生率。结果:A组和B组腹腔及切口感染发生率比较无显著差异(P>0.05),但两组均显著低于C组(P<0.05);A组和B组术后住院时间比较无显著差异(P>0.05),但均显著少于C组(P<0.05);A组、B组及C组术后体温恢复时间比较无显著差异(P>0.05);A组和B组肛门排气时间比较无显著差异(P>0.05),但两组均显著低于C组(P<0.05);B组术后不良反应发生情况高于A组和C组,但无显著差异(P>0.05)。结论:聚维酮碘稀释液能有效预防坏疽性阑尾炎伴穿孔术后腹腔及切口感染,显著缩短患者住院时间且不良反应发生率低,值得临床推广。

Objective：To investigate the clinical effect on gangrenous perforated appendicitis with postoperative abdominal cavity and incision infection by washing abdominal cavity with povidone iodine diluent. Methods：120 patients of Gangrenous perforated appendicitis treating with the surgical treatment in our hospital were selected as the research object,they were respectively given povidone iodine diluent,metronidazole and physiological saline for washing abdominal cavity and incision during operation.Comparatively analyzed postoperative abdominal cavity and incision infection status,time of body temperature returned to normal,postoperative hospital stay,and adverse reactions,and anus exhausting time of the three groups. Results：The incidence of abdominal cavity and incision infection had no significant difference between the povidone iodine group and metronidazole group（P0.05）,and it was significantly lower than the physiological saline group,the difference was significant（P0.05）;The body temperature of the three groups returned to normal time had no significant difference（P0.05）;The average time of hospital stay of povidone iodine group and metronidazole group were significantly shorter than that of the physiological saline group（P0.05）,and there was no significant difference between povidone iodine group and metronidazole group（P 〈0.05）;The anus exhausting time had no significant difference between the povidone iodine group and metronidazole group（P 〈0.05）,and it was significantly lower than the physiological saline group,the difference was significant（P 〈0.05）;The incidence of postoperative adverse reaction of metronidazole group was higher than that of povidone iodine group and physiological saline group,but there was no significant difference（P 〈0.05）. Conclusion：Povidone iodine diluent washing abdominal cavity can effectively reduce incidence rate of postoperative abdominal cavity and incision infection of the gangrenous perforated appendicitis,and the operation is simple,it has less adverse reaction,and worth of clinical promotion and application.