我院2013～2015年质子泵抑制剂应用的调查分析

Investigation and analysis of the application of proton pump inhibitors in our hospital during 2013～2015

目的：调查和分析我院2013~2015年质子泵抑制剂（PPIs）应用情况,了解我院质子泵抑制剂用药趋势,为临床合理用药提供参考。方法：在2013~2015年,利用医院阳光用药监控平台统计质子泵抑制剂的应用品种、年消耗量、销售金额,根据文献资料中的限定日剂量法（Defined Daily Dose,DDD）,得出用药频度（DDDs）、日均费用（DDDc）、序号比值等,进行综合分析和讨论。结果：2012~2014年我院质子泵抑制剂总的销售金额逐年增多。注射用奥美拉唑钠、注射用兰索拉唑占每年销售金额前两名,金额总体比例在下降。注射用泮托拉唑钠、注射用埃索美拉唑钠总体比例在一定程度上呈现增长趋势。用药频度最高的为兰索拉唑片。超过半数品种的序号比值接近1。结论：多数质子泵抑制剂日均费用与用药频度同步性较好,用药基本合理。

Objectiv：To investigate and analyze the application of proton pump inhibitors（PPIs） in our hospital during the period of2013~2015 to clear the tendency of drug use,and to provide reference to rational drug use in clini. Methods：During the period 2013~2015,to make statistics of the variety,annual consumption amount and sales amount of proton pump inhibitors on the Sunshine Medication Monitoring platform,and to work out the defined daily doses（DDDs）,daily costs（DDDC）and the ratio of sales volume sequencing to that of DDDs,and by using the method of the defined daily dose（DDD）in the literature,and then synthetically discuss and analyze them. Results：From 2012 to 2014,the total sale amount of proton pump inhibitors increased year by year.The sales amount of omeprazole sodium for injection and lansoprazole for injection keep the top two for three years,while their constituent ratio were decreased. And the constituent ratio of Pantoprazole Sodium for Injection、Esomeprazole Sodium for Injection,to a certain extent,showing a growing trend. The DDDS of Lansoprazole Tablets is the highest. The ratio of sales volume sequencing to that of DDDs of more then half of PPIs was close to 1. Conclusion：Most of the sales amount and DDDs of proton pump inhibitors in the hospital had a good consistency in DDDc and DDDs.The use of PPIs is basic reasonabl.