肝功能检验应用于肝炎患者的临床价值

Clinical value of hepatic function test in patients with hepatitis

目的经调查探究和分析肝功能检验应用于肝炎患者的临床价值。方法随机选择2014年4月—5月在本院接受肝功能检验的100例患者纳入观察组,同时随机选取同期体检的85例肝功正常者纳入对照组。检测并比较两组白蛋白(ALB)、血清胆固醇(CHO)、总胆汁酸(TBA)以及血清胆碱酯酶(CHE)水平情况。同时比较观察组不同child分级下的相关指标水平。结果观察组患者的ALB、CHO、CHE水平分别为(31.5±4.7)g/L、(2.86±0.30)mmol/L、(2651±254)U/L显著低于对照组检验水平,而TBA水平为(51.46±13.55)μmol/L明显高于对照组,差异在统计学上有意义(P<0.05);经比较Child A级患者相比,Child B级、Child C级ALB、CHO、CHE水平检验结果显著较低,而TBA显著较高,差异在统计学层面具显著性(P<0.05)。结论 ALB、CHO、TBA以及CHE各项肝功检测的临床指标可作为评价患者病情变化情况的关键性依据,肝功检验的临床意义显著。

Objective To investigate the clinical value of hepatic function test in patients with hepatitis. Methods 100 cases with hepatitis in our hospital from April 2014 to May 2014 were selected randomly as observation group. 85 healthy check-up people were selected as control group. Compare the ALB,CHO,TBA,CHE of the two groups and related indicators of different Child-Pugh of the observation group. Results ALB,CHO,CHE of observation group were（ 31. 5± 4. 7） g / L,（ 2. 86 ± 0. 30） mmol / L,（ 2651 ± 254） U / L,obviously lower than those the control group. And TBA level was（ 51. 46 ± 13. 55） μmol / L,obviously higher than that of control group,the difference was statistically significant（ P〈0. 05）. Compared with Child A patients,ALB,CHO and CHE level of Child B and Child C were obviouly lower than those the control group. But TBA was obviously higher,the difference was statistically significant（ P〈0. 05）. Conclusion Clinical indicators of liver function test as ALB,CHO,TBA and CHE can be used as key basis to evaluate situation changes of patients and the clinical significant of hepatic function test is remarkable.