肌钙蛋白Ⅰ水平检测对急诊心房颤动患者的临床作用

Clinical utility and prognostic significance of measuring troponin I levels in patients presenting to the emergency room with atrial fibrillation

目的:探讨肌钙蛋白I(TnI)水平检测对急诊心房颤动患者的临床作用及预测价值。方法:回顾性分析我院662例急诊心房颤动患者的临床资料,依据TnI水平将患者分为A组220例(TnI轻度升高)、B组283例(TnI正常)、C组159例(未检测TnI)。主要终点为1年内全因死亡及急性心肌梗死(AMI)。结果:A组患者复合终点事件、AMI发生率显著高于B组和C组(P<0.01),但3组患者1年内总体病死率比较差异无统计学意义。结论:TnI轻度升高与冠状动脉疾病发生率及AMI发生率增加有关。

Objective：To explore the clinical effect and predictive value of troponin I（TnI）in the patients presented to the emergency department with atrial fibrillation.Method：The clinical data of 662 patients with atrial fibrillation who were treated in our hospital were retrospectively studied.All the patients were divided into 3groups according to the level of TnI：group A（n=220,mildly elevated）,group B（n=283,normal）and group C（n=159,the level of TnI didn＇t measured）.The primary endpoints were all-cause mortality and acute myocardial infarction（AMI）in one year.Result：The composite endpoint and the rate of AMI in group A were significantly higher than that in group B and group C（P〈0.01）.The overall mortality rate had no significant difference between three group within 1years.Conclusion：TnI with mild elevating is associated with a greater incidence of coronary artery disease and a higher incidence of AMI.