摘要
目的:探讨妇科中成药应用中不良反应(ADR)发生的特点及一般规律,为妇科临床合理使用中成药提供参考依据。方法:收集我院ADR报告信息系统2008-2015年上报的妇科ADR报告,从中提取所有中成药ADR报告病例,对其进行统计、分析。结果:41例中成药ADR中无严重的ADR;新的一般的ADR 24例,占58.54%;一般的ADR 17例,占41.46%;用药后1~3 d ADR发生率高,占97.6%;以口服给药(19例,占46.3%)和阴道给药(15例,占36.6%)引发的ADR为主;ADR主要累及消化系统反应(29.79%)、全身性反应(19.15%)和生殖系统(17.02%)等。结论:妇科使用中成药相对安全,但对于某些特殊的病例仍需谨慎,注意区别用药。
OBJECTIVE:To explore the characteristics and regularity of ADR induced by gynecological Chinese patent medicine,and to provide reference for rational use of gynecological Chinese patent medicine. METHODS:ADR reports were collected from gynecological ADR reporting information system of our hospital during 2008-2105;all ADR cases of Chinese patent medicine were collected and analyzed. RESULTS:No severe ADR was found among 41 cases of Chinese patent medicine-induced ADR,24 cases of new and common ADR(58.54%),17 cases of common ADR(41.46%);the incidence of ADR was in high level 1-3 d after medicating,being 97.6%. Main routes of administration were oral administration(19 cases,46.3%)and vaginal administration(15 cases,36.6%)in ADR cases. Clinical manifestations were gastrointestinal reaction(29.97%),systemic reaction(19.15%)and mild injury of reproductive system(17.02%),etc. CONCLUSIONS:Chinese patent medicine is relatively safety in gynecological department. However,caution should be exercised in special cases and different medication.
出处
《中国药房》
CAS
北大核心
2016年第17期2355-2357,共3页
China Pharmacy
关键词
中成药
不良反应
妇科
Chinese patent medicine
ADR
Gynecology department